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Ministerio de Ciencia e Innovación - Instituto de Salud Carlos III
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Research areas: Schizophrenia

Esquizofrenia

Schizophrenia is a priority research objective within the CIBERSAM. One of the most serious mental disorders and one that causes a high degree of disability, economic cost, and family suffering. The structure of the Centro de Investigación Biomédica en Red de Salud Mental incorporates a broad network of basic and clinical centres in which the national groups with the most schizophrenia research experience participate. Their collaboration is making it possible to provide a multidimensional approach to the complex problems related to the origin, course, and treatment of this disease. The CIBERSAM’s research is enabling remarkable advances in that knowledge and have resulted in important publications in journals with maximum international impact.

These advances include:

  • Obtaining a broad sample of patients with first psychotic episodes and organising their evolutive study.
  • Studying genetic, neurophysiologic, neuroimaging (structural, neurochemical, and functional), and biochemical variables in the initial phases of psychosis.
  • Study of the neurobiologic (genetic, neuroimaging, and neurophysiologic) bases of the different symptomatologic phenotypes of schizophrenia.
  • Studying the neurobiologic (neuroimaging, neurophysiologic, and cognitive) and clinical response phenotypes prior to different drug treatments.
  • Investigating the efficacy and effectiveness of psychotherapeutic treatments in combination with standard drug treatments in schizophrenia.
  • Studying the repercussions of schizophrenia on health status, psychosocial adjustment, quality of life, individual levels of disability, and patterns of service use on the part of those patients and their influence on comorbidity.

Co-ordination and Member Groups