Therapeutic Innovation

The enormous cost caused by mental illnesses is due to the high incidence and chronicity of some of them, as well as to the low efficacy of the drugs used for their treatment. The Therapeutic Innovation programme is a transversal programme with high quality and international visibility and channels CIBERSAM's efforts in the identification of new targets and therapeutic strategies in order to improve existing treatments. The programme integrates basic and clinical groups and develops translational and back-translational research, also working on the improvement of experimental models of mental illness. The programme has a long tradition in the identification and development of new therapeutic strategies, both pharmacological and non-pharmacological.

Lines of research

  • Study of the mechanism of action of drugs active in the Central Nervous System. Identification of new therapeutic targets.
  • Design and evaluation of new pharmacological and non-pharmacological treatment strategies.
  • Study of the physiopathology of psychiatric diseases, including genetic bases.
  • Design of new diagnostic and therapeutic tools in experimental models of mental illness.
  • Study of the neurobiological bases of resistance to treatments and the mechanism of action of new therapeutic strategies.


Main ResearcherConsortium InstitutionRegionsDetails
Esther Berrocoso Dominguez Universidad de Cádiz. Facultad de Medicina Andalucía View group
Benedicto Crespo Facorro Hospital Universitario Marqués de Valdecilla Cantabria View group
Eduard Vieta Pascual Hospital Clínico y Provincial de Barcelona Cataluña View group
Juan Salvador Nácher Roselló Universidad de Valencia C. Valenciana View group
José Javier Meana Martínez UPV Universidad del País Vasco/EHU País Vasco View group
Juan Carlos Leza Cerro U.C.M. Facultad de Medicina Madrid View group
Manuel Desco Menéndez Hospital General Universitario Gregorio Marañón Madrid View group
Analía Bortolozzi Biasoni Instituto de Investigaciones Biomédicas de Barcelona Cataluña View group
Diego José Palao Vidal Corporación Sanitaria Parc Taulí- Fundación I3PT Cataluña View group